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Updated: Jun 2, 2025

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大核细胞中α-Actinin-1 缺乏导致血小板数量低,血小板功能障碍和线粒体功能障碍

Xiangjie Lin1, Hanchen Gao1, Min Xin2

  • 1Department of Hematology, Zhejiang Key Laboratory for Precision Diagnosis and Treatment of Hematological Malignancies, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Blood advances
|January 15, 2025
PubMed
概括

巨核细胞中的α-actinin-1缺乏导致血小板数量低下和血小板功能受损. 这通过影响线粒体生物能学和细胞骨重塑来影响血静和血栓形成.

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