术后食道癌患者症状的多中心研究:一个网络分析
Furong Chen1, Zhenrong Shen2, Ying Xiong2
1School of Nursing, Guangzhou Medical University, Guangzhou, Guangdong Province, China.
概括
在食道癌症后的手术中,确定了诸如反流疼痛,饮食,口腔干燥症等症状集群. 针对酸性消化不良和胃烧是管理患者症状负担的关键.
科学领域:
- 在瘤学瘤学.
- 症状科学 症状科学
- 术后护理 术后护理
背景情况:
- 食道癌 (EC) 手术导致显著的症状负担.
- 了解症状的相互关系对于手术后有效的患者管理至关重要.
研究的目的:
- 在手术后的第一周内,探索食道癌症患者的症状集群.
- 调查这些术后症状之间的相互关系.
主要方法:
- 在501名食道癌症患者中使用EORTC QLQ-OES18的横截面调查.
- 探索性因子分析和网络分析被用于识别症状集群和关系.
- 在手术后一周内,从中国的一个多中心项目中招募了患者.
主要成果:
- 他们发现了三个不同的症状集群:"反流疼痛"",饮食"和"口腔干燥症".
- 哨兵症状包括酸/胆反流,饮食困难和口腔干燥.
- 酸性消化不良/胃灼热成为核心症状,口腔干燥作为桥梁症状.
结论:
- 针对酸/胆反流,饮食困难和口腔干燥的干预措施对于减轻症状负担至关重要.
- 解决酸性消化不良和胃灼热对于破坏不同症状集群之间的联系至关重要.
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