在中国,延长乳腺癌查超过45-64岁:成本效益分析
Nuopei Tan1, Changfa Xia1, Xinxin Yan1
1Office of Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Cancer letters
|January 15, 2025
概括
对于中等风险的中国女性来说,从35岁到64岁的两年一次的乳腺癌查提供了最具成本效益的策略. 这种方法平衡了好处和危害,与国家卫生倡议保持一致.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 卫生经济学 卫生经济学
背景情况:
- 在中国,乳腺癌 (BC) 查的最佳年龄尚未确定.
- 目前的查指南可能无法充分体现中国人口的好处或成本效益.
研究的目的:
- 评估调整中国妇女乳腺癌查年龄的益处,危害和成本效益.
- 确定两年一次的乳腺癌查计划的最佳开始和停止年龄.
主要方法:
- 成本效益分析比较不同的查年龄场景 (从35岁开始与45岁相比,在64岁停止与79岁相比).
- 增量成本效益比率 (ICER) 和质量调整寿命年 (QALY) 的评估.
- 评估过度诊断率和错误阳性结果.
主要成果:
- 两年一次的查比每年一次的查更具成本效益.
- 将开始年龄降低到35岁,导致每QALY的ICER为12,746美元,低于18,346美元的门.
- 将戒烟年龄延长到64岁以后,增加了伤害 (错误的阳性),而没有显著的额外好处,使64岁成为最佳戒烟年龄.
结论:
- 对于35-64岁的平均风险女性,每两年进行一次乳腺癌查是中国最具成本效益的策略.
- 这一战略与国家宫癌和乳腺癌查计划保持一致.
- 这些发现提供了基于证据的建议,以优化乳腺癌查政策.
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