脉冲波速率用于查冠状动脉疾病的准确性:系统性审查和元分析
Carla-Geovanna Lever-Megina1, Iván Cavero-Redondo1, Celia Álvarez-Bueno2
1CarVasCare Research Group, Facultad de Enfermería de Cuenca, 16733 Universidad de Castilla-La Mancha , Cuenca, Spain.
Diagnosis (Berlin, Germany)
|January 15, 2025
概括
脉冲波速度 (PWV) 显示出作为检测冠状动脉疾病 (CAD) 的非侵入性方法的希望. 这一系统性审查表明,PWV可以有效地选CAD,从而有可能改善患者的治疗结果和医疗保健效率.
科学领域:
- 心脏病学 心脏病学
- 诊断的准确性 诊断的准确性
- 医疗成像医学成像
背景情况:
- 冠状动脉疾病 (CAD) 是心血管事件的主要原因,患病率高,医疗费用高.
- 目前的CAD查方法具有侵入性和昂贵性,需要采用替代方法.
- 非侵入性技术对于早期检测和预防心血管事件至关重要.
研究的目的:
- 评估脉冲波速度 (PWV) 的诊断准确性,以检测疑似冠状动脉病患者的冠状动脉病 (CAD).
- 为了比较PWV与黄金标准诊断方法的疗效,血管造影.
- 确定PWV作为CAD的非侵入性查工具的潜力.
主要方法:
- 一个系统的审查和对比PWV和血管造影用于CAD检测的研究的元分析.
- 在PubMed,Scopus和Web of Science数据库中进行文献搜索,截至2024年8月.
- 使用QUADAS-2工具进行质量评估,使用Deeks方法进行出版偏差评估.
主要成果:
- 包括八项横截面研究,通过PWV和血管学同时测量CAD.
- 在检测CAD时,PWV的诊断几率比 (dOR) 为3.61.
- 这种dOR表明PWV具有显著的能力来识别CAD的存在或不存在.
结论:
- 脉冲波速度 (PWV) 表明检测冠状动脉疾病 (CAD) 的可能性很高.
- 实施PWV作为查技术可能有利于怀疑CAD的患者.
- PWV为CAD查提供了提高医疗保健资源利用效率的潜力.
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