动态重新配置的声流体元表面用于亚波长粒子操纵和组装
Sushruta Surappa1, Suraj Pavagada1, Fernando Soto1
1Bio-Acoustic MEMS in Medicine (BAMM) Lab, Canary Center at Stanford, Department of Radiology, School of Medicine, Stanford University, California, CA, USA.
Nature communications
|January 15, 2025
概括
研究人员开发了一种可重新配置的声流体元表面,用于精确的微观粒子操纵. 这项技术可以实时控制液体中的粒子定位和图案,并可用于生物分析和材料科学.
科学领域:
- 声学流体学 声学流体学
- 材料科学 材料科学 材料科学
- 生物技术是生物技术.
背景情况:
- 精确操纵微观粒子在各种科学领域至关重要.
- 现有的粒子操纵方法在灵活性和实时控制方面可能受到限制.
研究的目的:
- 为精确的微观粒子捕获和定位提供动态重新配置的声流体元表面.
- 为了证明平台在微流体系统中操纵颗粒和生物细胞的实用性.
主要方法:
- 在被动膜共振器阵列中利用声学结构相互作用.
- 产生局部化的,可重新配置的静止声波.
- 采用声波辐射力用于亚波长粒子操纵.
主要成果:
- 在个人和集体尺度上实现实时,可重新配置的粒子模式.
- 证明成功地捕获和丰富微型珠和生物细胞.
- 在低于2MHz的调动频率下运行元表面.
结论:
- 开发的声流体超表面为粒子操纵提供了一个多功能和生物相容的平台.
- 该技术显示出高通量生物分析应用的巨大潜力,包括稀有细胞丰富.
- 允许精确组装合颗粒和先进的微流体应用.
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When a fluid is in constant acceleration, the pressure and buoyant force equations are modified. Suppose a beaker is placed in an elevator accelerating upward with a constant acceleration, a. In the beaker, assume there is a thin cylinder of height h with an infinitesimal cross-sectional area, ΔS.
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01:17Steady, Laminar Flow Between Parallel Plates
Understanding steady, laminar flow between parallel plates is essential for analyzing and designing flow in narrow rectangular channels, commonly found in various water conveyance and drainage systems. The Navier-Stokes equations govern fluid motion and are generally challenging to solve due to their nonlinearity. However, simplifications are possible in certain cases, like the steady laminar flow between parallel plates. For this scenario, we assume steady, incompressible, laminar flow.
01:27Laminar Flow
Laminar flow represents a smooth, orderly fluid motion where particles move along parallel paths, resulting in minimal mixing between layers. Streamlined particle paths characterize this flow regime and occur under conditions where viscous forces dominate over inertial forces. The distinction between laminar, transitional, and turbulent flow is primarily determined by the Reynolds number, a dimensionless quantity calculated as: