Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Phylogenetic Trees03:21

Phylogenetic Trees

45.1K
Phylogenetic trees come in many forms. It matters in which sequence the organisms are arranged from the bottom to the top of the tree, but the branches can rotate at their nodes without altering the information. The lines connecting individual nodes can be straight, angled, or even curved.
45.1K
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

5.7K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.7K
Phylogeny01:23

Phylogeny

43.6K
Phylogeny is concerned with the evolutionary diversification of organisms or groups of organisms. A group of organisms with a name is called a taxon (singular). Taxa (plural) can span different levels of the evolutionary hierarchy. For instance, the group containing all birds is a taxon (comprising the class Aves), and the group of all species of daisies (the genus Bellis) is a taxon. Phylogenies can likewise include just one genus (i.e., depict species relationships) or span an entire kingdom.
43.6K
Multi-species Conserved Sequences02:51

Multi-species Conserved Sequences

3.9K
Next-generation sequencing technologies have created large genomic databases of a variety of animals and plants. Ever since the human genome project was completed, scientists studied the genome of primates, mammals, and other phylogenetically distant living beings. Such large-scale  studies have provided new insights into the evolutionary relationship between organisms.
Although the genome of each species varies greatly from each other, a few sequences are highly conserved. Such conserved...
3.9K
Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

7.0K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
7.0K
Structural Protein Function01:56

Structural Protein Function

2.7K
2.7K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Fast and accurate multiple-protein-sequence alignment at scale with FAMSA2.

Nature biotechnology·2026
Same author

PhyloCNN: Improving Tree Representation and Neural Network Architecture for Deep Learning from Trees in Phylodynamics and Diversification Studies.

Systematic biology·2025
Same author

An nf-core framework for the systematic comparison of alternative modeling tools: the multiple sequence alignment case study.

NAR genomics and bioinformatics·2025
Same author

A resource of RNA-binding protein motifs across eukaryotes reveals evolutionary dynamics and gene-regulatory function.

Nature biotechnology·2025
Same author

HGTs are not SPRs: In the Presence of Ghost Lineages, Series of Horizontal Gene Transfers do not Result in Series of Subtree Pruning and Regrafting.

Molecular biology and evolution·2025
Same author

Accelerating Maximum Likelihood Phylogenetic Inference via Early Stopping to Evade (Over-)optimization.

Systematic biology·2025
Same journal

Plasmonic nanocomposite helices for weather-adaptive LiDAR function.

Nature communications·2026
Same journal

Multidirectional strain-insensitive stretchable RF electronics.

Nature communications·2026
Same journal

In-scanner thoughts contribute to resting-state functional connectivity.

Nature communications·2026
Same journal

Metal-center electron affinity modulates multicolor electrochromism in 2D conjugated metal-organic frameworks.

Nature communications·2026
Same journal

Hyperbranched dielectric polymer networks exhibiting giant energy storage density at 250 °C.

Nature communications·2026
Same journal

3D nanoprinting of metals by spatiotemporally confined hot electrons via multiple-electron excitations in nanocrystals.

Nature communications·2026
查看所有相关文章

相关实验视频

Updated: Jun 2, 2025

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
08:57

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

Published on: August 14, 2018

15.8K

多条链:通过结构信息来促进家族遗传学分析.

Athanasios Baltzis1, Luisa Santus1,2, Björn E Langer1

  • 1Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr. Aiguader 88, Barcelona, 08003, Spain.

Nature communications
|January 15, 2025
PubMed
概括
此摘要是机器生成的。

提高家族遗传树的可靠性至关重要. 将蛋白质序列和结构数据结合起来,可以增强引导分支支支值,从而获得更准确的进化见解.

更多相关视频

A Practical Guide to Phylogenetics for Nonexperts
12:00

A Practical Guide to Phylogenetics for Nonexperts

Published on: February 5, 2014

35.3K
The ITS2 Database
16:17

The ITS2 Database

Published on: March 12, 2012

30.7K

相关实验视频

Last Updated: Jun 2, 2025

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
08:57

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

Published on: August 14, 2018

15.8K
A Practical Guide to Phylogenetics for Nonexperts
12:00

A Practical Guide to Phylogenetics for Nonexperts

Published on: February 5, 2014

35.3K
The ITS2 Database
16:17

The ITS2 Database

Published on: March 12, 2012

30.7K

科学领域:

  • 计算生物学 计算生物学
  • 生物信息学是一种生物信息学.
  • 进化生物学 进化生物学

背景情况:

  • 可靠的支部支估计对于准确的家族遗传树来说至关重要.
  • 传统的仅使用序列数据的引导方法可以通过和来限制.

研究的目的:

  • 为了提高家族遗传学分支支持估计的可靠性.
  • 整合序列和结构信息,以进行增强的遗传学分析.

主要方法:

  • 开发了一种名为 multistrap. 的新方法.
  • 系统地比较同类的分子内结构距离.
  • 使用组合序列和结构数据计算树状距离矩阵.

主要成果:

  • 结构距离变化显示的和度低于基于序列的哈明距离.
  • 来自组合数据的族系树与仅序列的树有很强的相似之处.
  • 组合的序列和结构引导支持值可以改善正确和不正确的分支之间的区别.

结论:

  • 多条链方法有效地提高了引导链分支支持值.
  • 利用预测和实验的3D蛋白质结构可以提高遗传学准确性.
  • 这种方法提供了一种更强大的方法来推断进化关系.