面部评估方法抑制糖化和衰老效应,以及糖化和衰老参数之间的相关性
Qin Zhang1, Dangdang Cheng2,3, Feifei Wang4
1Shanghai Jiyan Biomedical Development Co., Ltd., 9th Floor, Building B, No.999 Huaxu Road, Shanghai, 201702, China. zhangqin01@botanee.com.
Scientific reports
|January 15, 2025
概括
这项研究开发了新的方法来测量皮肤糖化和老化. 该产品显示出显著的抗糖化和抗衰老益处,特别是通过减少高级糖化最终产品 (AGEs) 来改善皮肤色调.
科学领域:
- 皮肤病学 皮肤病学
- 化品科学 化品科学
- 生物化学 生物化学
背景情况:
- 先进的糖化最终产品 (AGEs) 与皮肤衰老有关.
- 需要使用非侵入性方法来评估面部AGE和抗衰老效应.
- 了解糖化和特定衰老迹象之间的联系对于化品开发至关重要.
研究的目的:
- 开发和验证用于评估面部抗糖化和抗衰老作用的体内方法.
- 调查面部AGE水平与可见皮肤衰老参数之间的相关性.
- 评估一种化品在减少糖化和改善皮肤衰老迹象方面的有效性.
主要方法:
- 使用AGE阅读器测量脸部和手臂的AGE水平,建立面部评估的相关性.
- 使用非侵入式探针和VISIA CR.评估了产品的7天抗糖化作用和56天抗衰老作用.
- 评估皮肤参数,包括色调 (亮度,黄色,光泽),纹理 (弹性,坚硬度,毛孔) 和水分.
主要成果:
- 通过强烈的面部-手臂AGE相关性,验证了AGE阅读器可靠地检测面部AGE.
- 证明了该产品显著的7天抗糖化和56天抗衰老作用.
- 与质地和水分相比,AGE水平和皮肤色调参数之间的相关性更强.
结论:
- 开发了有效的体内方法,用于对抗糖化和抗衰老要求的化品产品评估.
- 测试产品在减轻糖化和逆转皮肤衰老迹象方面表现出显著的有效性.
- 糖化显著影响皮肤色调,强调其在衰老过程和化品干预中的重要性.
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