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Updated: Apr 12, 2026

High-throughput Identification of Synergistic Drug Combinations by the Overlap2 Method
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基于基于元路的异质图形神经网络预测药物组合副作用

Leixia Tian1,2,3, Qi Wang4, Zhiheng Zhou2,3

  • 1Beijing School, Beijing, 100088, China.

BMC bioinformatics
|January 15, 2025
PubMed
概括

预测联合药物治疗的有毒副作用至关重要. 使用基于metapath的聚合嵌入模型在单一药物副作用异质信息网络 (MAEM-SSHIN) 和组合药物和副作用异质信息网络 (GCN-CSHIN) 的图形卷积网络的新型框架提高了准确性.

关键词:
组合药物 组合药物是一种药物.图表 卷积网络 卷积网络不同质的信息网络 不同质的信息网络超级疗法 (Metapath) 是指一种超级疗法 (Metapath).预测副作用的预测

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