在美国成年人中,特定领域的体力活动与甘油三糖 (TyG) 指数之间的关联:来自NHANES 2007-2018年的证据
1Department of Neurology, Jinshan Hospital, Fudan University, 1508 Longhang Road, Jinshan District, Shanghai, China, 201508. jsyyyao6@126.com.
BMC public health
|January 15, 2025
概括
休时间的体力活动与较低的甘油三糖 (TyG) 指数有关,甘油三糖指数是胰岛素抵抗的标志物. 与职业和交通相关的活动没有显示任何关联,这表明有针对性的运动建议对代谢健康至关重要.
科学领域:
- 内分泌学和新陈代谢学
- 公共卫生和流行病学
- 运动生理学 运动生理学
背景情况:
- 甘油三糖指数 (TyG) 是一种已验证的胰岛素耐药性的指标.
- 提升的TyG指数与心血管疾病,中风,抑郁症和阿尔茨海默病的风险增加有关.
- 了解不同体力活动领域对TyG指数的影响对于公共卫生战略至关重要.
研究的目的:
- 调查特定领域中等或强烈强度体力活动 (MVPA) 与美国成年人TyG指数之间的关联.
- 为了确定与职业相关的MVPA (O-MVPA),与交通相关的MVPA (T-MVPA) 或休时间 MVPA (LT-MVPA) 是否对TyG指数产生不同的影响.
- 探索MVPA和TyG指数之间的关系中的潜在效果修改和媒介,如BMI.
主要方法:
- 来自美国国家健康和营养检查调查 (NHANES) (2007-2018) 数据的分析,包括12,069名参与者.
- 使用全球体力活动问卷对O-MVPA,T-MVPA和LT-MVPA的评估.
- 应用加权多变量线性回归和倾向得分匹配 (PSM),以及分层和调解分析.
主要成果:
- 休时间MVPA (LT-MVPA) 与TyG指数 (β = -0.10,P < 0.001) 显示出显著的负相关性.
- 与职业相关的MVPA (O-MVPA) 和与运输相关的MVPA (T-MVPA) 与TyG指数没有显著的相关性.
- 在女性,高收入人群和非吸烟者中,LT-MVPA与降低的TyG指数之间的关联更为强烈. 体重指数 (BMI) 显著调解了这种关系.
结论:
- 休时间的体力活动与美国成年人较低的TyG指数独立相关.
- 与职业和运输相关的体力活动似乎不会影响TyG指数.
- 公共卫生指南应强调休时间的体育活动,以控制胰岛素耐药性和相关疾病风险.
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