腰椎间盘的 Artcure 扩散贴片治疗的中长期功能结果:哪种更有可能需要手术?
Zekeriya Ersin Çelen1, Furkan Hanege2, Soner Sarı2
1Department of Orthopaedics and Traumatology, Yalova Training and Research Hospital, Yalova, Turkey. drersincelen@gmail.com.
BMC musculoskeletal disorders
|January 15, 2025
概括
在中长期内,Artcure扩散贴片 (ADP) 为腰椎椎间板 (LDH) 提供了一种安全有效的治疗方法. 较高的度预测了更大的手术需求,需要更密切的患者监测.
科学领域:
- 整形外科 整形外科 整形外科
- 神经外科 神经外科
- 疼痛管理 疼痛管理
背景情况:
- 腰椎间盘 (LDH) 是腰部疼痛的一个常见原因.
- 通过皮肤治疗的系统,如Artcure扩散贴片 (ADP),是LDH的新兴治疗方法.
- 之前对LDH的ADP的研究集中在早期结果上.
研究的目的:
- 评估LDH患者ADP治疗的中长期功能结果.
- 为了确定LDH的ADP治疗后手术干预的预测因素.
主要方法:
- 一组270名单级LDH患者接受了透皮ADP.
- 用奥斯威斯特残疾指数 (ODI) 和视觉模拟尺度 (VAS) 测量疼痛的结果.
- 用密歇根州立大学 (MSU) 的分级系统对椎间板裂变的严重程度进行了分类.
主要成果:
- 观察到VAS和ODI得分在1个月和最终随访后显著降低 (p < 0.001).
- 平均随访时间为43.8个月.
- 在研究期间,只有7.0%的患者 (19/270) 需要手术.
- 多变量分析确定MSU等级≥2作为手术的重要预测因素 (HR:7.32,p=0.004).
结论:
- 单剂量ADP是一种安全和可行的选择,用于管理单级LDH,产生积极的功能和疼痛改善.
- 患有MSU 2或3级的患者需要更密切的监测,因为未来手术需要的可能性增加.
更多相关视频
06:05Operational and Intervention Effects of Targeted Tuina in Lumbar Intervertebral Disc Degeneration Model Rabbits
Published on: July 21, 2023
473
03:24Author Spotlight: Development and Application of a Novel Suture Technique for Annular Fibrosus Repair in Percutaneous Transforaminal Endoscopic Discectomy
Published on: January 26, 2024
696
相关概念视频
Herniated Intervertebral Disc l: Introduction
Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
Degenerative Disc Disease I: Introduction
Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
