相关实验视频

Updated: May 5, 2026

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye

Published on: June 20, 2015

使用600kHz的扫描源光学连贯性断层扫描仪对状网状结构动态运动进行体积成像

Zhaoyu Gong¹, Yaping Shi¹, Jian Liu¹

¹Department of Bioengineering, University of Washington, Seattle, WA 98105, USA.

Biomedical optics express

|January 16, 2025

概括

这项研究引入了体积成像来评估椎网状 (TM) 运动,改善了水性幽默排水评估. 新方法提高了检查吞吐量,并为诊断出流异常提供了宝贵的生物力学见解.

科学领域:

眼科医生眼科眼科
生物医学工程生物医学工程
医疗成像医学成像

背景情况:

椎间板状网络 (TM) 运动对于水性幽默排水和维持眼内压力至关重要.
目前的相位敏感光学连贯性断层扫描 (OCT) 方法使用有限的横向扫描来评估TM运动,限制吞吐量.
描述TM生物力学对于评估水性流出系统功能至关重要.

研究的目的:

引入第一个体积成像方法来评估TM运动.
为了提高TM生物机械成像的检查吞吐量.
为了更全面地了解TM运动,用于诊断眼和其他外流异常.

主要方法:

开发了一种用于TM运动评估的新型体积OCT成像方法.
实施重复体积扫描以观察连续的TM频段.
利用定制的体积注册算法进行运动工件校正,并基于与心跳相关的OCT相位动态进行TM边界识别的自动分段算法.
通过拼接多个扫描来扩大视野.

主要成果:

在健康受试者中证明了体积TM运动成像的可行性.
通过拼接体积扫描揭示了TM运动的显著空间变化.
证实了开发的算法能够纠正运动文物并准确地细分TM的能力.

结论:

拟议的体积成像方法大大提高了TM生物力学评估的检查吞吐量.
这种方法为科学洞察和诊断价值提供了前所未有的能力,用于识别水性流出异常.
卷度TM运动成像在理解和诊断影响眼内压力的疾病方面取得了重大进展.

更多相关视频

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

Simultaneous Brightfield, Fluorescence, and Optical Coherence Tomographic Imaging of Contracting Cardiac Trabeculae Ex Vivo

Simultaneous Brightfield, Fluorescence, and Optical Coherence Tomographic Imaging of Contracting Cardiac Trabeculae Ex Vivo

Published on: October 2, 2021

相关概念视频

Electron Microscope Tomography and Single-particle Reconstruction

Electron Microscope Tomography and Single-particle Reconstruction

Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...

Computed Tomography

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...

Imaging Studies III: Computed Tomography

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...