牛奶样本中的残留抗生素:评估孟加拉国的风险和流行率

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Farhana Rinky^1,2, Asma Rahman³, Sompa Reza¹

¹Institute of Nutrition and Food Science, University of Dhaka, Dhaka, Bangladesh.

Heliyon

|January 16, 2025

概括

在所有牛奶样本中发现了氧化环素 (OTC),其他兽医抗生素也被检测到. 虽然没有确定直接风险,但持续暴露在牛奶中的这些抗生素残留物引起了公众健康的担忧.

科学领域:

食品科学食品科学食品科学
分析化学分析化学
公共卫生公共卫生

背景情况:

兽医抗生素对动物健康至关重要,但可能导致牛奶中的残留物.
监测牛奶中的抗生素残留物对于食品安全和公共卫生保护至关重要.
了解多种抗生素残留物的患病率和相关性对于风险评估至关重要.

研究的目的:

在各种牛奶类型中分析五种常见的兽医抗生素 (四环素,氧四环素,多西环素,四环素,恩洛夫洛素).
估计与检测到的抗生素残留物相关的风险,并调查它们之间的相关性.
为了评估孟加拉国达卡的牛奶安全性,关于兽药污染.

主要方法:

使用RP-HPLC分析了27个牛奶样本 (原料,加工,消毒,UHT,调味).
检测到四环素 (TC),氧环素 (OTC),多环素 (DOX),环素 (CTC) 和恩洛夫洛素 (ENR).
皮尔森的相关性测试用于抗生素残留的相关性和风险评估.

主要成果:

在100%的样本中检测到氧化四环素 (OTC);在较低的百分比中发现了四环素 (CTC),恩洛夫洛素 (ENR),四环素 (TC) 和多环素 (DOX).
多种抗生素残留在UHT和调味牛奶中很常见;37.04%超过了MRL,44.44%接近极限.
在TC,CTC,DOX和ENR之间发现了显著的正相关性,但与OTC没有.

结论:

持续暴露在牛奶中检测到的抗生素残留物中,尽管没有直接的风险,但值得关注公共卫生问题.
遵守戒备期和严格的质量控制对于牛奶安全至关重要.
该研究强调需要对乳制品供应链中的兽药残留物进行警监测.

关键词:

高性能液体色谱学高性能液体色谱学牛奶牛奶牛奶牛奶剩余的抗生素剩余的抗生素风险分析风险分析

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