在儿科患者中冠状动脉的异常主动脉起源
Tam T Doan1,2, Charles Puelz2, Craig Rusin2
1Coronary Artery Anomalies Program, Division of Cardiology, Texas Children's Hospital, 6651 Main Street MC-E1920, Houston, TX 77030 USA.
Current pediatrics reports
|January 16, 2025
概括
冠状动脉的异常大动脉起源 (AAOCA) 需要仔细评估风险. 新的方法,如压力输液成像和计算建模,有助于管理AAOCA患者并预防心脏突然死亡.
科学领域:
- 心脏病学 心脏病学
- 遗传性心脏病是一种先天性心脏病.
- 医疗成像医学成像
背景情况:
- 冠状动脉的异常大动脉起源 (AAOCA) 是一种带有不同风险的先天性心脏缺陷.
- 异常的左冠状动脉从右大动脉鼻 (L-AAOCA) 与动脉间的过程构成突发心脏死亡 (SCD) 的高风险.
- 目前的指导方针建议对高风险的L-AAOCA进行运动限制和手术.
研究的目的:
- 提出一种当代的风险评估方法和AAOCA患者的管理.
- 突出高级成像和建模在评估AAOCA中的作用.
- 为AAOCA患者的临床决策提供信息.
主要方法:
- 关于AAOCA的当前文献和指导方针的审查.
- 在AAOCA中讨论压力输液成像的发现.
- 探索用于风险分层的计算建模技术.
主要成果:
- 动脉间流行的L-AAOCA与高SCD风险有关,需要进行干预.
- 在输液异常的基础上,塞普塔尔和相邻的L-AAOCA也可能需要进行外科手术.
- 异常的右冠状动脉从左大动脉鼻 (R-AAOCA) 有较低的风险;压力 perfusion 成像有助于缺血的识别.
- 成功的手术干预可以解决AAOCA患者的输液异常.
- 计算机建模在识别AAOCA的风险特征方面显示出有前途.
结论:
- 压力输液成像对于在介绍和干预后评估AAOCA是有价值的.
- 计算建模有可能提高对AAOCA的理解和管理.
- 整合成像和建模的综合方法是最佳AAOCA患者护理的关键.
相关概念视频
Coronary Circulation
2.2K
The heart, an organ critical to survival, gets nourishment not from the blood it pumps but from a separate circulation system known as coronary circulation. This is the shortest circulation in the body and is responsible for supplying the heart with the nutrients it needs to function effectively.
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
2.2K
The Arch of Aorta
553
The coronary arteries, originating from the ascending aorta, bifurcate from two sinuses located within the ascending aorta. Positioned just above the aortic semilunar valve, these sinuses house essential aortic baroreceptors and chemoreceptors, crucial for maintaining cardiac function. The left coronary artery and the right coronary artery branch off from the left posterior and anterior aortic sinuses, respectively.
Encircling the heart, the coronary arteries form a ring-like structure before...
Encircling the heart, the coronary arteries form a ring-like structure before...
553
Thoracic Aorta
360
The thoracic section of the aorta begins at the T5 vertebra and extends to the T12 level at the diaphragm, initially progressing through the mediastinum to the left of the spinal column. Throughout its course in the thoracic segment, the thoracic aorta emits various offshoots known collectively as visceral and parietal branches. The branches that predominantly supply blood to visceral organs are termed visceral branches and include bronchial, pericardial, esophageal, and mediastinal arteries,...
360
The Aorta
619
The aorta is the largest artery in the human body. It originates from the left ventricle of the heart and extends down to the abdomen, where it splits into two smaller arteries. Structurally, it can be divided into four main parts: the ascending aorta, the aortic arch, the thoracic aorta, and the abdominal aorta.
The average diameter of the aorta is approximately 2-3 cm, but the size can vary depending on the section of the aorta and the individual's age, sex, and body size. The aorta is...
The average diameter of the aorta is approximately 2-3 cm, but the size can vary depending on the section of the aorta and the individual's age, sex, and body size. The aorta is...
619
Abdominal Aorta
609
Once the aorta traverses the diaphragmatic plane at the aortic hiatus, it is known as the abdominal aorta. This anatomical structure is positioned leftward of the spinal column, encased within a cocoon of adipose tissue behind the peritoneal cavity. It terminates at the L4 vertebra, where it splits into the common iliac arteries. Prior to this bifurcation, the abdominal aorta gives rise to several vital branches.
The celiac trunk, a singular artery, divides into the left gastric artery, which...
The celiac trunk, a singular artery, divides into the left gastric artery, which...
609
Physiology of the Heart: The Cardiac Cycle
1.8K
The cardiac cycle describes the events from one heartbeat to the next. It includes three main phases: diastole, atrial systole, and ventricular systole, all driven by changes in chamber pressures and the function of heart valves.
Diastole: The Relaxation Phase
During diastole, all four heart chambers relax. The atrioventricular (AV) valves open, and the semilunar valves close. This phase sees the lowest chamber pressures, promoting ventricular filling. Venous blood enters the heart through the...
Diastole: The Relaxation Phase
During diastole, all four heart chambers relax. The atrioventricular (AV) valves open, and the semilunar valves close. This phase sees the lowest chamber pressures, promoting ventricular filling. Venous blood enters the heart through the...
1.8K


