纤维肌痛的重复性横性磁性刺激:我们还没有到达吗?
Jorge Dornellys da Silva Lapa1,2, Valquíria Aparecida da Silva3,4, Daniel Ciampi de Andrade5
1Neurosurgery Unit, Hospital de Cirurgia, Aracaju, Sergipe, Brazil.
Pain reports
|January 16, 2025
概括
重复的横磁刺激 (rTMS) 显示出对纤维肌痛的治疗有希望. 针对10 Hz运动皮质 (M1) 的特定参数似乎是持续缓解疼痛的最有效方法.
科学领域:
- 神经科学是一个神经科学.
- 神经学 神经学
- 疼痛管理 疼痛管理
背景情况:
- 纤维肌痛 (FM) 涉及与症状相关的不适应性皮质变化.
- 正在探索重复性横磁性刺激 (rTMS) 调节这些变化.
- 由于各种参数,目前关于rTMS对FM的疗效的证据是不确定的.
研究的目的:
- 审查用于纤维肌痛管理的rTMS现有证据.
- 系统地分析用于FM的rTMS试验中的刺激参数.
- 为了确定有效的rTMS协议来控制纤维肌痛的疼痛.
主要方法:
- 对rTMS治疗纤维肌痛的受控试验的叙述性综述.
- 在Medline和Embase数据库中进行了搜索.
- 包括每组≥10名参与者和≥3周治疗/随访的试验.
主要成果:
- 11项试验符合纳入标准;6项显示出积极结果.
- 背侧前额叶皮和初级运动皮层 (M1) 是常见的目标.
- 在10Hz的M1准与后前电流显示一致的积极结果.
- 每周/两周一次的维护会持续缓解疼痛效果.
结论:
- 在FM研究中,rTMS参数,结果和标准的异质性仍然存在.
- 优化刺激参数,特别是M1,对于止痛效果至关重要.
- 需要进行更大规模的多中心试验,以完善rTMS协议,以便更好地管理FM.
相关概念视频
Sensory Functions of the Skin
The skin is the largest organ of the human body and plays a crucial role in our sensory perception. It contains a vast network of sensory receptors that contribute to the skin's protective function by perceiving physical, biological, and environmental cues and generating relevant responses.
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
Muscle Stimulation Frequency
The contraction strength of muscles is regulated by motor neurons, which modulate the frequency of action potentials dispatched to the motor units based on the body's requirements. This process of varying the muscle stimulation frequency allows muscles to contract with a force that is precisely tailored to the needs of the moment, whether lifting a feather or a heavy box.
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...


