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上一次活检的类型是否会影响结合前列腺活检结果?
Gokhan Sonmez1, Abdullah Golbasi2, Unsal Bas3
1Erciyes University, Department of Urology, Devision of UroOncology, Kayseri, Turkey.
Prostate international
|January 16, 2025
概括
最初的前列腺活检的类型会影响诊断前列腺癌 (PCa) 的第二次活检的成功. 与融合活检相比,标准活检可能在随后的手术中提供更高的癌症检测率.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 诊断成像 诊断成像 诊断成像
背景情况:
- 融合前列腺活检 (FPB) 已用于前列腺癌 (PCa) 诊断十多年.
- 越来越多的患者先前有负FPB和持久的PCa怀疑需要考虑重复活检.
- 目前正在研究初始活检方法在指导后续诊断决策方面的有效性.
研究的目的:
- 评估第一个活检的类型 (标准与融合) 是否会影响第二次前列腺癌活检的结果.
- 为了确定初始活检策略是否会影响以前活检结果为负的患者的癌症检测率.
主要方法:
- 对275名男性患者 (40-75岁) 的回顾性分析,其活检史呈阴性,PSA升高或可疑的MRI.
- 患者根据他们的第一次活检分组:融合前列腺活检 (FPB) 或标准前列腺活检.
- 两组之间的人口统计,临床数据和前列腺癌检测率的比较.
主要成果:
- 与初始FPB (15.5%) 患者相比,首次活检是标准程序 (23%) 的患者更频繁地检测出前列腺癌.
- 研究小组在年龄,PSA水平,家族病史和前列腺体积方面相似.
- 观察到癌症检测率的统计学上显著差异 (p=0.044).
结论:
- 选择初始活检技术是规划第二次活检时的重要因素,对于有负面活检史和持续怀疑前列腺癌的患者.
- 标准的初始活检可能与随后的诊断程序中更高的检测率有关.
- 这一发现表明,在管理需要重复前列腺癌评估的患者时,需要考虑先前活检方法.
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