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手术后长时间使用抗生素并不能减少脊柱手术后手术部位感染
Sade Olatunbosun1, Brian L Hollenbeck1,2
1Division of Research, New England Baptist Hospital, Boston, Massachusetts, USA.
手术后的抗生素持续时间没有影响脊椎手术中的手术部位感染 (SSI) 率. 肥胖 (体重指数≥30) 被确定为SSI发展的重要危险因素.
科学领域:
- 整形外科手术 整形外科手术
- 神经外科 神经外科
- 传染性疾病 传染性疾病
背景情况:
- 在脊椎手术中,缺乏最佳的术后抗生素持续时间的证据.
- 了解风险因素和抗生素剂量对于改善患者的治疗结果至关重要.
研究的目的:
- 评估手术后抗生素治疗时间与脊椎手术后手术部位感染 (SSI) 率之间的关联.
- 在接受脊柱融合和/或减压的患者中确定SSI的危险因素.
主要方法:
- 从2018年1月到2023年7月,对5656次脊柱手术进行了回顾性队列研究.
- 对手术后抗生素持续时间 (≤24小时 vs>24小时) 和SSI发生率的分析.
- 单变量和多变量分析以确定SSI风险因素.
主要成果:
- 抗生素组之间的SSI发生率相似:0.50% (≤24小时) 和0.45% (>24小时) (p=0.769).
- 身体质量指数 (BMI) 超过30是SSI (OR2.54) 的唯一显著风险因素.
结论:
- 根据术后抗生素持续时间,没有观察到SSI发生率的显著差异.
- 增加的BMI (≥30) 是脊椎手术患者SSI的关键风险因素.
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