在帕金森病中,偏执和不寻常的感官体验是帕金森病的症状
Poppy Brown1,2,3, Daniel Freeman1,2, Bao Sheng Loe4,5
1Department of Experimental Psychology, University of Oxford, Oxford, UK.
Aging & mental health
|January 16, 2025
概括
精神病经历 (PEs) 在帕金森病 (PD) 中很常见,即使没有多巴胺作用药物治疗,也会影响近一半的患者. 抑郁和焦虑等心理因素可能会维持这些令人痛苦的PEs.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
背景情况:
- 帕金森病 (PD) 是一种神经退行性疾病,主要影响运动功能.
- 精神病体验 (PEs),包括偏执和不寻常的感官体验 (USE),在PD中越来越多地被认可.
- 关于PD中PEs的心理基础的研究有限.
研究的目的:
- 在患有PD的个体中全面评估与偏执狂和USE相关的频率,严重程度和痛苦.
- 确定与PD中PEs相关的心理变量,重点关注与非PD人群相关的过程.
- 为了比较PD中的偏执狂水平与年龄相匹配的对照.
主要方法:
- 对369名PD患者进行了问卷调查.
- 参与者的平均年龄为66岁,平均疾病持续时间为5年.
- 与年龄匹配的对照进行了比较,用于使用先前存在的数据进行的一组子集测量.
主要成果:
- 49%的PD参与者报告了USE,23%的人认为它们令人痛苦.
- 偏执在PD中低于对照组,但存在特定的担忧 (放弃,背叛).
- 抑郁,焦虑,孤独和耻辱感很高;心理变量与PEs有很强的相关性.
结论:
- 在PD中,PEs很常见,即使没有多巴胺作用药物治疗也会发生.
- 一个小组的个体经历痛苦的PEs没有通过当前的治疗解决.
- 抑郁和焦虑等认知情感因素可能会在PD中维持PEs,这表明干预目标.
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