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Updated: Jun 2, 2025

Characterization of Thymus-dependent and Thymus-independent Immunoglobulin Isotype Responses in Mice Using Enzyme-linked Immunosorbent Assay
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抗原亲缘关系和免疫接种地点决定了B细胞召回反应

Manon Termote1, Rafael C Marques1, Erik Hyllner1

  • 1Department of Microbiology, Tumor and Cell Biology, Division of Virology and Immunology, Karolinska Institutet, 171 65 Solna, Sweden.

Cell reports
|January 16, 2025
PubMed
概括

设计有效的HIV-1疫苗需要高抗体突变. 这项研究表明抗原亲和力和增强位置影响B细胞反应,指导未来的疫苗开发以向抗体多样化.

关键词:
B细胞召回反应的回应.CP: 免疫学 免疫学艾滋病毒-1疫苗 艾滋病毒-1疫苗抗原亲和力是一种亲和力.发芽中心的发芽中心.生殖中心加油,生殖中心加油.记忆 B 细胞 B 细胞二次生殖中心.顺序免疫接种 顺序免疫接种

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