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Updated: Jun 2, 2025

Combining Single-molecule Manipulation and Imaging for the Study of Protein-DNA Interactions
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Combining Single-molecule Manipulation and Imaging for the Study of Protein-DNA Interactions

Published on: August 27, 2014

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蛋白质目标搜索扩散-关联/解离 DNA结合部位周围的自由能量景观与侧边序列

Biao Wan1, Jin Yu2

  • 1Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou, Zhejiang, China.

Biophysical journal
|January 17, 2025
PubMed
概括

这项研究模拟了DNA上的蛋白质扩散,揭示了键和静电相互作用如何控制结合和滑动. 蛋白质的运动和DNA序列影响结合亲和力和种群分布.

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