运动期间腿部血流与血流限制:补偿性心血管机制的证据和影响
Stuart P S Mladen1, Stacey P A Forbes1, Abby K Zedic1
1School of Kinesiology and Health Studies, Queen's University, Kingston, Ontario, Canada.
Journal of applied physiology (Bethesda, Md. : 1985)
|January 17, 2025
概括
使用袖口膨胀低于60%的动脉阻塞压力 (AOP) 的血液流量限制 (BFR) 在运动期间损害了腿部的血液流量. 然而,随着时间的推移,由于腿部血管导电率的增加,这种限制会随着时间的推移而减少,因而因人而异.
科学领域:
- 运动生理学 运动生理学
- 心血管监管 监管心血管系统
- 血液流动动力学 血液流动动力学
背景情况:
- 血液流量限制 (BFR) 训练是提高肌肉适应性的热门训练.
- 较低的动脉封闭压力 (AOP) 对行使肢体输液的确切影响尚不清楚.
- 以前的假设表明,即使在中度AOP水平下,也会显著减少 perfusion.
研究的目的:
- 为了验证近位四肢袖口膨胀率为40%的AOP是否有效地降低了炼腿部血流 (LBF).
- 为了研究运动期间在LBF上不同AOP (20%和40%) 的剂量反应关系.
- 检查与BFR持续炼期间的LBF变化和补偿机制的时间进程.
主要方法:
- 18名健康参与者在25%的峰值工作负载下进行了膝盖曲/延伸炼.
- 双边大腿手被膨胀到0% (CTL),20%和40%的AOP.
- 测量了腿部的血流量 (多普勒超声波) 和心脏输出 (手指光透视图).
主要成果:
- 20%和40%的AOP都显著减少了以剂量依赖的方式炼LBF.
- 在整个炼过程中,LBF限制的程度逐渐下降 (从37%降至16%在40%的AOP).
- 腿部血管导电率 (LVC) 的补偿性增加减弱了BFR效应,具有显著的个体变异性.
结论:
- 气动袖口膨胀率在20%和40%的AOP确实会损害炼LBF,但随着时间的推移,这种影响会减弱.
- 增加的LVC是一个关键的补偿机制,尽管它的有效性在个体之间有所不同.
- 补偿反应的个体差异可能会影响肌肉适应BFR训练.
相关概念视频
Blood Flow
66.7K
Blood is pumped by the heart into the aorta, the largest artery in the body, and then into increasingly smaller arteries, arterioles, and capillaries. The velocity of blood flow decreases with increased cross-sectional blood vessel area. As blood returns to the heart through venules and veins, its velocity increases. The movement of blood is encouraged by smooth muscle in the vessel walls, the movement of skeletal muscle surrounding the vessels, and one-way valves that prevent backflow.
66.7K
Exercise and Cardiovascular Response
722
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
722
Autoregulation of Blood Flow
2.2K
Autoregulation mechanisms are characterized by their inherent capacity for self-regulation without necessitating specific nervous stimulation or endocrine control. These mechanisms facilitate the adjustment of blood flow and, therefore, perfusion specific to each tissue region. This self-regulation encompasses chemical signals and myogenic controls.
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation....
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation....
2.2K
Pathophysiology of Cardiac Performance
524
Typical heart performance is influenced by heart rate, rhythm, myocardial contraction, and metabolism or blood flow. The cardiac muscle exhibits distinct electrophysiological features, including pacemaker activity and calcium channel control, which play a vital role in the heart's response to various drugs. The autonomic nervous system, comprising the sympathetic and parasympathetic branches, regulates heart rate. Sympathetic activation increases heart rate, while parasympathetic activation...
524
Cardiac Output II: Effect of Stroke Volume on Cardiac Output
643
Cardiac output (CO), the amount of blood the heart pumps per minute, is a parameter in cardiovascular physiology determined by stroke volume and heart rate. Stroke volume, the amount of blood pushed from one of the ventricles per heartbeat, is influenced by preload, afterload, and contractility.
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
643
Imbalances in Cardiac Output
1.3K
The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
1.3K


