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Updated: Sep 11, 2026

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通过化学信息学方法识别葡萄糖-6-酸脱酶 (G6PD) 抑制剂

Srilatha Mundla1, Madhu Sudhana Saddala2

  • 1Department of Biotechnology, Sri Venkateswara University, Tirupati, Andhra Pradesh, India.

Critical reviews in oncogenesis
|January 17, 2025
PubMed
概括

研究人员通过向葡萄糖-6-酸脱酶 (G6PD),一种对癌细胞生长至关重要的酶,确定了潜在的新型癌症药物. 这些新型抑制剂对未来的癌症治疗开发有希望.

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Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...