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Updated: Jul 20, 2026

Comprehensive DNA Methylation Analysis Using a Methyl-CpG-binding Domain Capture-based Method in Chronic Lymphocytic Leukemia Patients
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在IgG4相关的胆管炎和原发性硬化胆管炎的表观遗传年龄加速和甲基化差异

Alexandra Noble1, Rodrigo Motta1, Silvia Cabras1

  • 1Translational Gastroenterology and Liver Unit, John Radcliffe Hospital, Headley Way, Headington, Oxford, OX3 9DU, UK.

Clinical epigenetics
|January 17, 2025
PubMed
概括

这项研究揭示了IgG4-相关胆炎 (IgG4-SC) 和原发性硬化胆炎 (PSC) 的新型表观遗传变化,包括IgG4-SC.生物衰老加速. 这些发现提供了对疾病机制的见解,并突出了遗传影响,特别是在HLA区域.

关键词:
年龄加速的加速度.通过DNA甲基化.基因表观时钟是什么?哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈在IgG4-RD的研究中,在Infinium甲基化EPIC阵列中使用.公共服务中心 (PSC)

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