身体活动,维生素D和全因/心血管死亡率:一项针对中国老年人的前性研究
Mingrui Chen1, Ling Cheng2, Sisi Yang2
1School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
BMC geriatrics
|January 17, 2025
概括
在中国老年人中,定期体力活动与较低的死亡风险有关,而维生素D起着调解作用. 这项研究强调了维生素D.
科学领域:
- 老年学是一门学科.
- 营养生物化学 营养生物化学
- 公共卫生 公共卫生
背景情况:
- 身体活动被认为与减少全因和心血管死亡率有关.
- 关于身体活动对80岁以上成年人死亡率的影响的研究有限.
研究的目的:
- 研究身体活动,维生素D水平和中国老年人死亡率之间的关联.
- 确定维生素D在体力活动和死亡率之间的关系中的中介作用.
主要方法:
- 利用中国长度健康长寿调查 (CLHLS) 中2863名老年人的数据.
- 使用标准化得分评估身体活动,并测量血清25-氧维生素D水平.
- 采用多变量调整的考克斯回归和调解分析来检查关联和调解效应.
主要成果:
- 较高的体力活动得分与较高的维生素D度相关.
- 无论是体力活动还是维生素D水平,都显示出与全因和心血管死亡率的反向关联.
- 维生素D介导了体力活动与所有原因死亡率之间的联系的7.76%,以及心血管死亡率的4.13%.
结论:
- 身体活动显著降低了中国老年人的全因和心血管死亡风险.
- 维生素D在这种关系中起着重要的调解作用,特别是在家务和物护理等活动中.
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