一项系统的流行病学趋势分析研究,研究了全球多发性骨髓瘤负担和29年的预测
Qianru Hou1, Xinyang Li2, Huanxin Ma1
1Department of Hematology, Shengjing Hospital of China Medical University, No. 39 Huaxiang Road, Tiexi District, Shenyang, 110021, Liaoning, China.
Scientific reports
|January 17, 2025
概括
多发性骨髓瘤的发病率和负担在全球范围内不断增加,特别是在高收入国家. 预测表明,到2050年,病例,流行率和死亡率将继续上升.
科学领域:
- 血液瘤学 血液瘤学
- 流行病学 流行病学
- 全球健康 全球健康
背景情况:
- 多发性骨髓瘤是一种显著的血液性恶性瘤,具有相当大的全球健康影响.
- 了解疾病负担趋势对于公共卫生规划和资源分配至关重要.
研究的目的:
- 利用最新的2021年疾病,伤害和风险因素研究全球负担数据分析多发性骨髓瘤的全球,区域和国家负担.
- 检查多发性骨髓瘤发病率,患病率,残疾调整寿命年 (DALYs) 和死亡率从1990年到2021年的趋势.
- 预测到2050年多发性骨髓瘤负担的未来趋势.
主要方法:
- 利用了2021年全球疾病,伤害和风险因素负担研究的数据.
- 分析了发病率,流行率,DALY和死亡率,包括95%的不确定性间隔.
- 根据人口,年龄和流行病学因素探索趋势,并预测未来的负担.
主要成果:
- 在2021年,全球多发性骨髓瘤发病率为148,755例;死亡率达到116,360,年龄标准化率为每10万人1.37.
- 从1990年到2021年,发生率,流行率和DALYs的持续增加被观察到.
- 在高收入国家,疾病负担最高,但在低收入国家,发病率正在上升.
结论:
- 多发性骨髓瘤负担在全球范围内不断增加,对医疗保健系统产生重大影响.
- 低收入国家的发病率上升需要有针对性的公共卫生干预措施.
- 未来的预测表明,多发性骨髓瘤发病率,流行率和死亡率的持续上升趋势.
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