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相关概念视频

Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
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Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

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The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
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Major Hormones and Their Functions01:27

Major Hormones and Their Functions

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Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
318
Insufficient Sleep and Sleep Deprivation01:13

Insufficient Sleep and Sleep Deprivation

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Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
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Hormonal Regulation01:40

Hormonal Regulation

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Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
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相关实验视频

Updated: Jun 2, 2025

Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model
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Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model

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地铁工人的轮班工作,甲状腺功能和肝功能.

F Yu1, J Liu2, T Qu1

  • 1Department of Occupational and Environmental Health, Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, PR China.

Occupational medicine (Oxford, England)
|January 17, 2025
PubMed
概括
此摘要是机器生成的。

轮班工作与地铁工人的性酸酶 (ALP) 水平较高有关. 这种效应部分归因于甲状腺激素的变化,特别是总三甲状腺素 (TT3) 和自由甲状腺素 (FT4).

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Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments
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Author Spotlight: Accurately Assessing Thyroid Hormone-Driven Motor Alterations in Mouse
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科学领域:

  • 职业健康 职业健康 职业健康
  • 内分泌学 在内分泌学.
  • 肝病学 肝病学是一种肝病学.

背景情况:

  • 轮班工作是肝损伤的已知危险因素.
  • 轮班工作对肝功能和潜在机制的确切影响仍然不完全理解.

研究的目的:

  • 检查轮班工作和肝功能参数之间的关系.
  • 调查甲状腺功能指标在这种关联中的潜在调解作用.

主要方法:

  • 对724名地铁工人进行了一项横截面研究.
  • 使用多变量线性回归和调解分析来评估关联和调解效应.

主要成果:

  • 轮班工作与性酸酶 (ALP),三甲胺总量 (TT3) 和自由甲状腺素 (FT4) 水平的升高相关.
  • 甲状腺激素 (TT3和FT4) 部分调解了轮班工作和ALP水平增加之间的关联,分别占39%和29%.
  • 对某些肝酶的关联在30岁以上的工人和酒精使用者中更为明显.

结论:

  • 轮班工作与地铁工人的ALP水平增加有关.
  • 甲状腺功能指标,特别是TT3和FT4,在轮班工作和高ALP之间的联系中发挥着部分调解作用.