在支气管镜检查之前, nebulized budesonide 的贡献,这是一个前性的临床研究
Guoxin Zhang1, Hu Yu2, Li Zhang1
1Department of Respiratory and Critical Care Medicine, Tianjin University Chest Hospital, Thoracic Clinical College of Tianjin Medical University, Tianjin Chest Hospital, No. 261 Taier Zhuang Nan Road, Jinnan District, Tianjin 300051, China.
Postgraduate medical journal
|January 17, 2025
概括
将布德索尼德添加到雾化利多卡因中,可显著改善灵活支气管镜检查 (FB) 期间的患者舒适性和安全性. 与单独利多卡因相比,这种组合疗法提高了程序效率和患者的耐受性.
科学领域:
- 肺部病理学 肺部病理学
- 麻醉学 麻醉学
- 胃肠病学 胃肠病学
背景情况:
- 具有局部麻醉的灵活支气管镜 (FB) 是一种常见的程序.
- 患者的不适和咳是FB期间的重大挑战.
- 目前的方法可能无法完全缓解患者的痛苦.
研究的目的:
- 为了评估在接受FB的患者中添加布塞索尼德到雾化利多卡因的疗效.
- 为了比较组合疗法与单独的 nebulized 利多卡因.
主要方法:
- 在局部麻醉下接受FB患者的随机研究.
- 两个组:组合 (布德索尼德 + 利多卡因) 与单独的利多卡因,两者都被雾化.
- 监测生命体征,咳,不适以及操作员满意度.
主要成果:
- 布塞尼德-利多卡因组显示血压降低,氧和度更高,咳和不适减少.
- 在组合组中观察到更高的操作员满意度和更短的程序时间.
- 对于重新操作的意愿或程序类型没有显著差异.
结论:
- 结合利多卡因的 nebulized budesonide 比单独的利多卡因对 FB 更有效.
- 这种组合可以提高患者的耐受性和程序效率.
- 当有意识的镇静不能实现时,为FB提供了优化的方法.
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