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缺血性中风后增强的神经发生:内源和外源干细胞之间的相互作用

Ruxu Geng1, Yuhe Wang1, Renzhi Wang1

  • 1Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

Neural regeneration research
|January 17, 2025
PubMed
概括

干细胞疗法通过刺激内源性神经干细胞来增强缺血性中风后的大脑修复. 结合外源和内源干细胞的策略显示出改善神经再生和功能恢复的前景.

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Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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