在患有炎症性肠道疾病的患者中是否需要进行例行听力查 - - 一项前性研究
Nayanika Reddy1, Vijendra S Shenoy2, Navya Parvathareddy1
1Department of Otorhinolaryngology and Head and Neck Surgery, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, India.
概括
炎症性肠病 (IBD) 患者,特别是性结肠炎 (UC) 患者,对听力损失的敏感性更高,特别是在8000 Hz时. 扭曲产品耳声发射 (DPOAE) 在检测亚临床听力损失方面比纯色调听力测量 (PTA) 更有效.
科学领域:
- 听力学 听力学是指听力学.
- 胃肠病学 胃肠病学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 炎症性肠病 (IBD) 包括慢性疾病,如性结肠炎 (UC) 和克罗恩病.
- 听力障碍是IBD潜在的肠外表现,但其听力学特征需要进一步调查.
- 了解IBD亚型与听力损失之间的关联对于全面的患者管理至关重要.
研究的目的:
- 为了比较不同类型的IBD患者的听力学概况.
- 调查IBD和听力损失之间的关联,考虑到疾病持续时间和年龄.
- 评估IBD患者听力损失的程度.
主要方法:
- 一项涉及120名受试者的研究,分为对照组和病例组.
- 根据活检,病例被分组为UC和克罗恩病.
- 听力评估使用纯音调听力测量 (PTA) 和扭曲产品耳声发射 (DPOAE),结果与疾病持续时间和年龄进行分析.
主要成果:
- 在UC和克罗恩病组中观察到8000Hz的轻度听力损失,UC中更明显.
- 在UC组中,PTA在频率上显示出更大的中位数dB损失,显着在1000,2000,4000和8000Hz.
- 在66.6%的耳朵中,DPOAE显示了8000Hz的缺席响应,明显高于PTA发现,在疾病持续时间较长 (> 5年) 和年龄较大 (> 30年) 的患者中,缺席响应增加.
结论:
- 与克罗恩病相比,性结肠炎病例对听力损失的易感性更高,特别是在8000 Hz时.
- 扭曲产品耳声发射 (DPOAE) 在诊断IBD患者的亚临床听力损失方面优于PTA.
- 在IBD中,听力损失可能与疾病持续时间和患者年龄有关,这凸显了需要听力学监测的必要性.
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