在COVID-19患者的软组织中自发出血的管理选择的比较
A E Tyagunov1,2, D Y Trudkov1,2, A Y Polyaev1,2
1Department of Faculty Surgery No. 1, Pirogov Russian National Research Medical University (Pirogov Medical University), Ostrovityanova Str., 1, Moscow, Russia, 117997.
Scientific reports
|January 17, 2025
概括
对于COVID-19患者自发软组织出血的治疗选择没有影响30天的存活率. 血管造影,栓塞或手术显示,这些危急患者的非手术治疗结果与非手术治疗结果类似.
科学领域:
- 医学研究 医学研究
- 关键护理医学 关键护理医学
- 放射学 放射学是一门学科.
背景情况:
- 自发软组织出血是重症COVID-19患者接受抗凝药治疗的严重并发症.
- 有效的管理策略对于提高这一脆弱群体的生存率至关重要.
研究的目的:
- 为了评估不同治疗方式对COVID-19患者的生存结果的影响,这些患者经历了自发软组织出血.
- 为了比较非手术管理 (NOM),血管造影 (AG) 与跨动脉栓塞 (TAE) 和开放手术 (OS) 在这个患者队列中的疗效.
主要方法:
- 一项回顾性单中心研究包括227名COVID-19患者在2020年3月至2022年3月期间自发软组织血瘤.
- 患者接受了NOM (n=144),AG (n=60,其中TAE在41) 或OS (n=23) 的治疗.
- 使用统计分析,包括多变量逻辑回归来评估30天死亡率.
主要成果:
- 治疗组之间没有观察到30天死亡率的显著差异 (p = 0.094).
- 多变量分析表明,与AG相比,OS和NOM都没有增加死亡风险 (分别为OR 1.53和1.39).
- 在CT上的超振并没有影响治疗策略对死亡率的影响.
结论:
- 选择治疗策略 (NOM,AG/TAE或OS) 并没有显著影响COVID-19患者自发软组织出血的30天生存期.
- 这些发现表明,当前的治疗选择为管理这种并发症提供了可比的生存益处.
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