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Updated: Jun 1, 2025

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甲状腺眼病的机制:TSH受体与IGF-1受体直接相互作用

Rauf Latif1,2, Mihaly Mezei1,3, Terry F Davies1,2

  • 1Department of Medicine, Thyroid Research Unit, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

Endocrinology
|January 17, 2025
PubMed
概括

甲状腺眼病 (TED) 涉及TSH受体 (TSHR) 和IGF-1受体 (IGF-1R) 之间的相互作用. 这项研究揭示了这些受体之间的直接物理连接,独立于β-arrestin,提供了新的治疗见解.

关键词:
胰岛素样生长因子1受体分子动力学分子动力学甲状腺眼睛疾病 甲状腺眼睛疾病甲状腺刺激激素受体受体跨膜域域是一个跨膜域.

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