铜(II) 复合物中异构体的异常变异性与1,8-bis(2-基) - 环
Milan Maďar1, Jan Faltejsek1,2, Hana Bušková2,3
1Department of Inorganic Chemistry, Faculty of Science, Charles University, Hlavova 8, 128 40 Prague 2, Czech Republic. kubicek@natur.cuni.cz.
Dalton transactions (Cambridge, England : 2003)
|January 17, 2025
概括
这项研究研究了1,8-bis(2-hydroxybenzyl) -cyclam的铜复合体 (CuII),揭示了具有不同结构和协调的多种异构体. 这些铜复合体表现出缓慢的相互转化,使不同物种的隔离和表征成为可能.
科学领域:
- 协调化学 协调化学
- 无机化学 无机化学
- 超分子化学 超分子化学
背景情况:
- 铜复合物对于放射诊断和放射治疗至关重要.
- 1,8-bis(2-基) 环联体 (H2L) 形成了多种不同的CuII复合体.
- 金属复合体中的同质性影响其特性和应用.
研究的目的:
- 研究CuII复合物的结构多样性和同质性,其中含有1,8-bis(2-基) - 环 (H2L).
- 描述溶液和固态中的单个异构体.
- 了解影响复杂稳定性和协调模式的因素.
主要方法:
- 高性能液体染色学 (HPLC) 用于异构体的分离.
- 紫外线可见光谱 (UV-VIS) 用于电子表征.
- 电化学测量以探测氧化还原特性.
- 对于固态结构的确定,进行X射线衍射分析.
- 理论计算 (计算化学) 支持实验发现.
主要成果:
- 观察到一种意想不到的异构体种类,它们在替代物定向,质子化状态和连接体密度上有所不同.
- 六坐标的trans-III同位素是最稳定和最常见的形式.
- 在溶液中确定了五坐标的cis-V异构体和其他形式.
- 在trans-III异构体中发现了弱轴协调,在cis-V异构体中发现了强的基底平面协调.
- 计算数据表明,内联的键稳定了该复合体,并表明了潜在的动态行为.
结论:
- 由于相互转换速度缓慢,H2L的CuII复合体表现出显著的异构性.
- 结构特征揭示了不同协调环境和同位素之间的稳定性差异.
- 内部分子相互作用和带灵活性在复合物的结构多样性和溶液中的行为中起着至关重要的作用.
更多相关视频
11:04Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides
Published on: September 7, 2019
9.1K
09:35Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
Published on: September 18, 2016
11.4K
相关概念视频
02:33Stereoisomerism of Cyclic Compounds
8.7K
In this lesson, we delve into the role of ring conformation and its stability, which determines the spatial arrangement and, consequently, the molecular symmetry and stereoisomerism of cyclic compounds. 1,2-Dimethylcyclohexane is used as a case study to evaluate the possible number of stereoisomers. Here, given the multiple (n = 2) chiral centers, there are 2n = 4 possible configurations that lack a plane of symmetry, as the ring skeleton exists in a non-planar chair conformation. In addition,...
8.7K
02:52Stereoisomerism
11.7K
Isomerism in Complexes
Isomers are different chemical species that have the same chemical formula.
Transition metal complexes often exist as geometric isomers, in which the same atoms are connected through the same types of bonds but with differences in their orientation in space. Coordination complexes with two different ligands in the cis and trans positions from a ligand of interest form isomers. For example, the octahedral [Co(NH3)4Cl2]+ ion has two isomers (Figure 1) In the cis...
Isomers are different chemical species that have the same chemical formula.
Transition metal complexes often exist as geometric isomers, in which the same atoms are connected through the same types of bonds but with differences in their orientation in space. Coordination complexes with two different ligands in the cis and trans positions from a ligand of interest form isomers. For example, the octahedral [Co(NH3)4Cl2]+ ion has two isomers (Figure 1) In the cis...
11.7K
02:37Disubstituted Cyclohexanes: cis-trans Isomerism
11.8K
Depending upon the different spatial orientation of the substituents, the disubstituted cycloalkanes exhibit two types of stereoisomers. The cis isomers have the substituents on the same side of the ring, whereas the trans isomers have the substituents on the opposite sides. These stereoisomers exhibit different physical properties and cannot be interconverted without breaking the carbon-carbon bonds.
In cyclohexane, the substituents can occupy different positions generating distinct isomers....
In cyclohexane, the substituents can occupy different positions generating distinct isomers....
11.8K
02:34Structural Isomerism
19.1K
Isomerism in Complexes
Isomers are different chemical species that have the same chemical formula. Structural isomerism of coordination compounds can be divided into two subcategories, the linkage isomers and coordination-sphere isomers.
Linkage isomers occur when the coordination compound contains a ligand that can bind to the transition metal center through two different atoms. For example, the CN− ligand can bind through the carbon atom or through the nitrogen atom. Similarly, SCN− can...
Isomers are different chemical species that have the same chemical formula. Structural isomerism of coordination compounds can be divided into two subcategories, the linkage isomers and coordination-sphere isomers.
Linkage isomers occur when the coordination compound contains a ligand that can bind to the transition metal center through two different atoms. For example, the CN− ligand can bind through the carbon atom or through the nitrogen atom. Similarly, SCN− can...
19.1K
02:30Stability of Substituted Cyclohexanes
12.3K
This lesson discusses the stability of substituted cyclohexanes with a focus on energies of various conformers and the effect of 1,3-diaxial interactions.
The two chair conformations of cyclohexanes undergo rapid interconversion at room temperature. Both forms have identical energies and stabilities, each comprising equal amounts of the equilibrium mixture. Replacing a hydrogen atom with a functional group makes the two conformations energetically non-equivalent.
For example, in...
The two chair conformations of cyclohexanes undergo rapid interconversion at room temperature. Both forms have identical energies and stabilities, each comprising equal amounts of the equilibrium mixture. Replacing a hydrogen atom with a functional group makes the two conformations energetically non-equivalent.
For example, in...
12.3K
01:18Aromatic Hydrocarbon Cations: Structural Overview
2.7K
Cycloheptatriene is a neutral monocyclic unsaturated hydrocarbon that consists of an odd number of carbon atoms and an intervening sp3 carbon in the ring. The three double bonds in the ring correspond to 6 π electrons, which is a Huckel number, and therefore satisfies the criteria of 4n + 2 π electrons. However, the intervening sp3 carbon disrupts the continuous overlap of p orbitals. As a result, cycloheptatriene is not aromatic.
Removing one hydrogen from the intervening CH2 group...
Removing one hydrogen from the intervening CH2 group...
2.7K