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Updated: Aug 19, 2026

Optimized LC-MS/MS Method for the High-throughput Analysis of Clinical Samples of Ivacaftor, Its Major Metabolites, and Lumacaftor in Biological Fluids of Cystic Fibrosis Patients
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在人类血和尿液基质中开发和验证一种高度灵敏的三元四元LC-MS/MS方法,用于确定贝克西沙林 (LP352)

Raja Reddy Kallem1, Maisy Yeager2, Rosa Chan1

  • 1Department of Clinical Pharmacology and Pharmacometrics, Longboard Pharmaceuticals, Inc. is a part of Lundbeck as a wholly owned subsidiary of Lundbeck LLC, La Jolla, California, USA.

Biomedical chromatography : BMC
|January 17, 2025
PubMed
概括

一种新的LC-MS/MS方法准确地量化了人体血和尿液中的5-HT2c受体激动剂贝克西沙林. 这种经过验证的方法支持临床开发治疗发育性和性脑病变 (DEE) 中的发作.

关键词:
迪斯 (Dees) 是一个法定债权.在 LCMS/MS 中使用.LP352 这是一个很好的方法.贝克西卡塞林是什么意思人类血的人类血.药物动力学 药物动力学

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Rapid Identification of Pathogens01:25

Rapid Identification of Pathogens

MALDI-TOF MS has transformed clinical microbiology by offering a rapid and reliable method for pathogen identification. The traditional approach to microbial identification typically involves time-consuming culture techniques and biochemical tests, which can delay the initiation of appropriate antimicrobial therapy. MALDI-TOF MS avoids these delays by using characteristic ribosomal protein mass patterns of microbial cells, enabling accurate species-level identification within minutes.Principle...