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Updated: Jun 21, 2026

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
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Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids

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基于三重形成核酸的光探针的设计,用于对双链RNA结构的强制间接传感

Yusuke Sato1, Takaya Sato2, En Ting Tabitha Lee2

  • 1Department of Chemistry, Graduate School of Science, Tohoku University, Aoba-Ku, Sendai, 980-8578, Japan. yusuke.sato.a7@tohoku.ac.jp.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry
|January 17, 2025
PubMed
概括

研究人员开发了新的三倍形成核酸 (TFP) 探针,用于检测双链RNA (dsRNA). 这些探测器利用光染料间歇和结合来进行敏感的dsRNA检测,有助于RNA结构分析.

关键词:
这是一种双链RNA.光探测器探测器可以发光.强迫的插曲是强迫的插曲.酸核酸是一种核酸.

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...