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Updated: Jun 1, 2025

Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity
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细胞内信号分子酸化的增加表明人类自身反应性B细胞的持续激活

Sanne Kroos1, Nienke J Blomberg1, Joanneke C Kwekkeboom1

  • 1Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.

European journal of immunology
|January 17, 2025
PubMed
概括

诸如类风湿性关节炎之类的自身免疫性疾病涉及自身反应性B细胞. 这项研究发现,这些B细胞表现出连续的激活信号,即使没有外部刺激,这表明抗原驱动的活动.

关键词:
B 细胞 B 细胞 B 细胞这是自身免疫力.细胞免疫学 细胞免疫学激酶激酶是一种激素.类风湿病学 类风湿病学

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