相关实验视频
Updated: Jun 1, 2025

08:40
Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
7.0K
在炎症性肠病发展之前的儿童的人类测量轨迹
Maiara Brusco De Freitas1, Gry Juul Poulsen1, Tine Jess1,2
1Center for Molecular Prediction of Inflammatory Bowel Disease, Department of Clinical Medicine, Aalborg University, Copenhagen, Denmark.
JAMA network open
|January 17, 2025
概括
患有炎症性肠病 (IBD) 的儿童在诊断前几年就表现出生长和营养受损. 营养查对于监测IBD儿童和确保诊断后健康发育至关重要.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 营养科学 营养科学
- 流行病学 流行病学
背景情况:
- 儿童期营养不良和生长不良会对儿童的健康产生重大短期和长期的后果.
- 早期识别营养状况受损对于及时诊断和治疗儿科炎症性肠病 (IBD) 至关重要.
研究的目的:
- 在儿科IBD诊断之前,评估儿童的人类学轨迹.
- 评估IBD诊断后儿童的生长恢复模式.
主要方法:
- 一项基于人口的队列研究分析了来自丹麦医疗出生登记册和国家儿童健康登记册的数据.
- 包括1997-2015年间出生的儿童,年龄在5-17岁之间被诊断为IBD.
- 在诊断前和诊断后比较人体测量 (身高,体重,BMI),与参考和兄弟种群进行比较.
主要成果:
- 被诊断为克罗恩病 (CD) 的儿童在诊断前3年显示体重和BMI下降,并在诊断前1年减少长度/身高.
- 患有性结肠炎 (UC) 的儿童在诊断前1年内体重和BMI下降.
- 诊断后仍然存在不良的人类测量趋势,CD儿童的恢复速度较慢.
结论:
- 儿科IBD发病可能在诊断前几年,由营养状况受损表明.
- 增长恢复通常发生在诊断和治疗开始后.
- 建议对有IBD的儿童进行定期的营养查,以支持健康的成年过渡.
相关概念视频
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
314
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
314
Inflammatory Bowel Disease II: Crohn's Disease
181
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
181
Anatomy of the Intestines
71.3K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
71.3K
Inflammatory Bowel Disease I: Ulcerative Colitis
134
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
134
Chronic Bowel Disorders: Introduction
386
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
386
Inflammatory Bowel Disease IV: Pharmacological Management
109
Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
Pharmacologic...
109

