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生殖系基因组编辑是影响人的还是影响身份的,这有什么意义吗?

Andrew McGee¹, Sinead Prince²

¹Australian Centre for Health Law Research, Faculty of Business & Law, Queensland University of Technology, Brisbane, Queensland, Australia.

|January 17, 2025

概括

关于生殖基因组编辑和胚胎选择的伦理含义仍在争论中. 虽然这两种方法都能预防遗传疾病,但由于基因组编辑风险,胚胎选择目前在伦理上更可取.

科学领域:

生物伦理学生物伦理学
遗传学遗传学是一个
哲学哲学是一个哲学.

背景情况:

关于生殖系基因组编辑是否影响人或影响身份存在争论.
这种区别影响了基因组编辑和胚胎选择的植入前遗传诊断 (PGD) 之间的伦理选择.
目的是防止或产生后代的特定条件,如囊性纤维化或聋.

研究的目的:

分析最近关于生殖系基因组编辑伦理的哲学观点.
确定影响人与影响身份的区别的伦理相关性.
为了比较基因组编辑和胚胎选择用于预防遗传疾病的伦理地位.

主要方法:

对近期关于生殖系基因组编辑的哲学文献进行审查和分析.
审查有关影响个人和影响身份的标准的论点.
在生殖目标的背景下对基因组编辑与胚胎选择的伦理评价.

主要成果:

影响个人和影响身份的观点都具有有效性.
当主要目标是健康的后代时,基因组编辑影响人的性质在伦理上变得不那么重要.
与基因组编辑相关的当前风险使其不如胚胎选择.

结论:

胚胎选择目前是比生殖系基因组编辑更道德的选择.
实现健康孩子的主要目标指导着这种道德偏好.
基因组编辑的持续风险需要谨慎,并支持像胚胎选择这样的既定方法.

关键词:

帕菲特 (Parfit) 是一个非常适合的品牌.胚胎选择胚胎选择基因组编辑-基因组编辑影响身份的行为.非身份问题是非身份问题.影响人‐影响人.植入前遗传诊断植入前遗传诊断

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