非吸烟者,非饮酒者,口腔状细胞癌患者是一个独特且具有临床意义的群体
Paul Mario Capanni1, Jeremey David McMahon2, Bilal Aslam-Pervez2
1Dental Graduate, University of Glasgow Dental School, 378 Sauchiehall Street, Glasgow, UK. paul.m.capanni@hotmail.com.
Oral and maxillofacial surgery
|January 17, 2025
概括
非吸烟者,非饮酒者是口腔状细胞癌 (OSCC) 患者的一个独特群体. 这项研究发现,他们往往是患有早期疾病和特定瘤部位的老年女性,与其他OSCC群体不同.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 口腔癌研究 在口腔癌研究.
背景情况:
- 口腔状细胞癌 (OSCC) 传统上与吸烟和饮酒有关.
- 越来越多的OSCC患者是非吸烟者和非饮酒者 (NSND).
- NSND OSCC患者的人口统计和特征需要进一步调查.
研究的目的:
- 分析NSND OSCC患者的人口统计和生存结果.
- 在OSCC人口中识别NSND个体的独特特征.
- 介绍迄今为止关于这个特定的OSCC群体最大的队列研究的发现.
主要方法:
- 541名OSCC患者的回顾性分析.
- 根据吸烟 (每周少于五支香烟) 和饮酒 (每周少于三支标准饮料) 的习惯进行分类.
- 评估瘤亚部位,阶段,转移,以及与危险因素状况相关的存活率.
主要成果:
- NSND患者主要是女性和老年人.
- 在NSND组中,早期疾病呈现更为常见.
- 与吸烟者/饮酒者群体相比,瘤部位有显著差异,有利于舌头,大膜和口腔粘膜.
结论:
- 在OSCC案件中,NSND个体构成了重要的和独特的人口.
- 这些患者具有独特的人口特征 (老年人,女性) 和早期疾病.
- 独特的瘤部位分布凸显了NSNDs作为口腔癌管理中的临床显著子组.
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