慢性子宫内膜炎和子宫内膜异位症:同一枚硬币的两面?
Dimitrios Rafail Kalaitzopoulos1, Ursula Catena2, Alexandra Kohl Schwartz3,4
1Department of Gynecology and Obstetrics, Cantonal Hospital of Schaffhausen, Geissbergstrasse 81, 8208, Schaffhausen, Switzerland. Dimitrios.Kalaitzopoulos@spitaeler-sh.ch.
Reproductive sciences (Thousand Oaks, Calif.)
|January 17, 2025
概括
患有子宫内膜异位症的女性患慢性子宫内膜炎的风险明显更高. 这项研究发现,在子宫内膜异位症患者中,慢性子宫内膜炎的患病率为28%,特别是在晚期,影响不孕症治疗.
科学领域:
- 生殖医学 生殖医学
- 妇科 妇科医生 妇科
- 传染性疾病 传染性疾病
背景情况:
- 慢性子宫内膜炎和子宫内膜异位症在不育患者中很常见.
- 这些条件之间的共存和关联尚未得到充分理解.
- 评估这种关联对于理解不孕症至关重要.
研究的目的:
- 系统地审查和元分析慢性子宫内膜炎和子宫内膜异位症之间的关联.
- 确定诊断为子宫内膜异位症的女性慢性子宫内膜炎的流行率.
- 评估对不孕症的影响.
主要方法:
- 在MEDLINE,Scopus和Cochrane数据库中进行系统电子搜索,截至2022年5月.
- 包括慢性子宫内膜炎在子宫内膜异位症患者中患病率的观察性研究.
- 使用纽卡斯尔-太华尺度进行质量评估;计算几率比率和聚合流行率.
主要成果:
- 六项研究被纳入了审查中;五项研究被纳入了元分析.
- 在患有子宫内膜异位症的女性中,慢性子宫内膜炎的总体患病率为28%.
- 发病率在晚期子宫内膜异位症阶段 (rASRM III-IV:43%) 与早期阶段 (rASRM I-II:25%) 相比较高.
- 分析显示,与对照组相比,子宫内膜异位症患者患慢性子宫内膜炎的风险显著增加 (OR=2.07).
结论:
- 患有子宫内膜异位症的女性患慢性子宫内膜炎的风险明显增加.
- 这些发现提高了对子宫内膜异位症和慢性子宫内膜炎病变的理解.
- 结果可以指导开发改善治疗策略的相关不孕症.
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