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Updated: May 26, 2026

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在最近的小皮下心脏病发作后",Cap"和"Track"发展的临床相关性

Yajun Cheng1,2, Carmen Arteaga-Reyes2, Una Clancy2

  • 1Department of Neurology, West China Hospital, Sichuan University, Chengdu, China.

Annals of neurology
|January 17, 2025
PubMed
概括

最近的小皮下心脏病发作 (RSSI) 后,新的MRI发现称为"帽子/轨道",表明功能不良和中风复发的风险更高. 这些标志物可能反映出渐进的小血管疾病损伤.

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Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
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An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
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A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...