预防性水态止痛可降低腹腔镜胆囊切除术患者的术后狂妄和应激反应
Weitao Zhang1, Yanni Yang2, Yuqiang Yan1
1Department of Anesthesiology, Xi'an Central Hospital No. 161, Xiwu Road, Xincheng District, Xi'an 710003, Shaanxi, China.
American journal of translational research
|January 17, 2025
概括
预防性水利摩尔镇痛有效地减少了腹腔镜胆囊切除术后的术后疼痛和压力. 这种方法也显著降低了手术后狂妄症的发生率,改善了患者的治疗结果.
科学领域:
- 麻醉学和疼痛管理
- 手术患者护理手术患者护理
- 神经科学和重症监护
背景情况:
- 手术后妄 (POD) 是手术后的一个常见并发症,特别是在老年患者中.
- laparoscopic胆囊切除术虽然侵袭性最小,但仍然可以引发显著的疼痛和压力反应.
- 有效的疼痛管理和减轻压力对于预防POD至关重要.
研究的目的:
- 为了研究预防性水利摩尔止痛对术后痴呆症的影响.
- 为了评估先发性水利摩尔对腹腔镜胆囊切除术患者应激反应的影响.
- 为了比较接受预防性水利摩和不接受治疗的患者之间的疼痛控制和妄发病率.
主要方法:
- 一项回顾性队列研究包括167名接受腹腔镜胆囊切除术的患者.
- 患者被分为观察组 (预防性水利摩尔) 和对照组.
- 评估了术后疼痛 (视觉模拟量表),压力标志物 (上腺素,上腺素,多巴胺) 和妄想发病率.
主要成果:
- 观察组在术后30分钟显示显著较低的视觉模拟量表得分 (P<0.001).
- 在观察组中,经手术后的上腺素,上腺素和多巴胺水平显著降低 (所有P<0.001).
- 在观察组中,术后妄想的发生率明显较低 (P<0.05). 较高的普罗波福和雷米芬坦尼尔剂量被确定为 Delirium 的危险因素.
结论:
- 预防性水利摩尔止痛是有效的减少术后疼痛和应激反应.
- 这种止痛策略显著降低了腹腔镜胆囊切除术后术后的发生率.
- 与传统方法相比,水利摩尔提供了优越的疼痛控制和有利的安全概况.
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