慢性病相关的 Pruritus 负担: 一项患者调查研究
Jeffrey Thompson1, Jennifer Kammerer2, Tasha Boshears1
1Real World Evidence, Oracle Life Sciences, Austin, TX.
Kidney medicine
|January 17, 2025
概括
慢性病相关的 (CKD-aP) 显著影响生活质量和透析治疗. 许多患者经历了不充分的症状管理和减少幸福感,尽管向医疗保健提供者报告.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 皮肤病学 皮肤病学
- 公共卫生 公共卫生
背景情况:
- 慢性病相关的 (CKD-aP) 是一种普遍且经常被忽视的疾病,影响慢性病 (CKD) 患者,特别是接受血液透析 (HD) 患者.
- 对患者的生活质量 (QoL) 和治疗坚持的重大负担需要更深入地了解他们的临床旅程.
研究的目的:
- 分析CKD-aP患者的临床治疗过程和的整体负担.
- 调查CKD-aP对医疗保健提供者的参与,治疗满意度和患者报告结果的影响.
主要方法:
- 从2021年12月到2022年5月,在美国进行了一项横截面的,患者报告的在线调查,对2021年12月至2022年5月期间在美国接受HD的成年患者进行了调查.
- 经过验证的患者报告的结果仪器被用于评估的特征,症状管理,医疗保健工作人员的参与,以及对HD,QOL,睡眠和工作生产力的影响.
- 使用双变量分析来检查的严重程度与CKD特异性QoL之间的关联.
主要成果:
- 在354名CKD-aP患者中,49%有中度和30%有严重的. 大约68%的人向卫生保健工作者报告了症状,其中55%的人接受了治疗建议,主要是局部乳液和皮质类固醇.
- 对治疗的满意度有限,口服处方的使用率低. 显著比例的患者 (23%) 缩短和 (17%) 错过了HD会议,因为.
- 更严重的CKD-aP与更糟糕的QOL,睡眠质量和功能/工作障碍显著相关 (所有P <.001或P <.05).
结论:
- 经常治疗CKD-aP不足,并严重干扰透析治疗,即使报告给医疗保健提供者.
- 在CKD-aP中恶化的严重程度直接与减少QoL,睡眠质量受损以及功能和工作能力降低相关.
- 需要改进管理策略,以减轻透析的CKD患者的的负担.
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