CYP24A1在 keloid 角质细胞中过度表达,其抑制会改变益菌性基因表达

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Updated: Jun 1, 2025

Isolation, Culture, and Characterization of Primary Dermal Fibroblasts from Human Keloid Tissue
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Isolation, Culture, and Characterization of Primary Dermal Fibroblasts from Human Keloid Tissue

Published on: July 28, 2023

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Jennifer M Hahn1, Kelly A Combs1, Caitlin M Phillips2

  • 1Department of Surgery, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH, 45267, USA.

Burns & trauma
|January 17, 2025
PubMed
概括

抑制维生素D代谢酶CYP24A1可能会通过降低profibrotic基因表达来减少 keloid 形成. 这表明CYP24A1抑制剂可能是 keloid 障碍的辅助疗法.

关键词:
24-基酶的使用方法在 CYP24A1 中.皮质 - 介质细胞过渡.凯洛伊德 (Keloid) 是一种类型的细胞.氨酸细胞 (keratinocyte) 是一种细胞.维生素D 维生素D是一种维生素.

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