患者和公众参与设计和协议开发的平台随机试验,以评估诊断测试,以优化抗微生物治疗 (PROTECT)
Martina Svobodova1, Liza Keating2, Melanie Gager2
1Centre for Trials Research, Cardiff University, Cardiff, Wales, CF14 4YS, UK.
NIHR open research
|January 17, 2025
概括
公众参与开发PROTECT试验总协议,确保了其可行性和公众的接受性. 患者和公众的意见塑造了抗菌药物管理干预,有效地解决了抗生素耐药性的问题.
科学领域:
- 医疗保健服务研究 医疗服务研究
- 抗微生物药物管理委员会
- 患者和公众参与.
背景情况:
- 该PROTECT试验旨在评估抗微生物管理干预措施,以减少急性疾病患者不必要使用抗生素.
- 患者和公众的参与是开发试验总体协议和研究应用程序的组成部分.
研究的目的:
- 评估抗微生物管理干预措施的有效性,实施和效率.
- 通过排除严重的细菌感染,安全地减少不必要的抗生素使用.
主要方法:
- 举办了三个与不同参与者的公众参与会议,包括年轻人,家长和那些有急诊室经验的人.
- 通过录制的电话会议会议收集数据,随后进行笔记和发现总结.
- 在2023年9月13日,2023年10月14日和2024年2月28日收集的数据.
主要成果:
- 在协议阶段的公众参与允许塑造和影响试验设计.
- 确定试验可行性,并了解公众对该干预措施的看法.
- 抗生素耐药性被确定为一个迫切的问题;对新技术的研究被认为是及时的.
结论:
- 具有实践经验的公共贡献者是试验团队的宝贵资源.
- 通过现有的英国公众参与小组进行招聘,确保了参与者的多样化代表性.
- 该项目是公众参与小组和包容性研究的实践者之间有效合作的典范.
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