在COVID-19之前和期间使用抗菌剂:来自108个退伍军人事务医疗中心的数据
Matthew Bidwell Goetz1, Tina Willson2, Michael A Rubin2
1VA Greater Los Angeles Healthcare System and David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Antimicrobial stewardship & healthcare epidemiology : ASHE
|January 17, 2025
概括
住院抗生素的使用最初在COVID-19期间上升,但随后下降到大流行前的水平. 到2022年,抗生素处方在COVID-19患者中较低,尽管设施级别的变化仍然存在.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 医疗保健服务研究 医疗服务研究
背景情况:
- 随着COVID-19的流行,住院患者的抗生素使用量增加.
- 疫情期间抗生素处方模式的变化需要调查.
研究的目的:
- 为了确定高水平的住院抗生素使用是否在流行后持续存在.
- 为了比较COVID-19患者和没有COVID-19患者的抗生素使用情况.
主要方法:
- 对108个退伍军人事务机构的回顾性队列分析.
- 从2016年到2022年检查了抗菌剂的使用,患者日和COVID-19护理.
- 按抗生素类分层计算的每1000个当前日 (DP) 的治疗日数 (DOT).
主要成果:
- 抗生素使用在2020年初急剧增加,但到年底总体下降.
- 在2022年,COVID-19患者的全系统抗生素使用量下降了9%.
- 设施级抗生素使用量有所不同,其中25%的COVID-19患者使用量更高.
结论:
- 总体而言,自疫情爆发以来,住院患者的抗生素使用量已经下降.
- 需要进一步的研究来解决设施层面的差异,并证明当前在COVID-19患者中使用抗生素的合理性.
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