在IgG4相关疾病中的临床和成像肺部表现
Jesica Romina Gallo1, Cristian Froullet2, Alejandro Varizat3
1From the Reumatología, Hospital Central de Reconquista, Santa Fe, Argentina.
计算机断层扫描 (CT) 扫描显示,在IgG4相关疾病 (IgG4-RD) 中,常见的肺肺发现. 在没有肺部感染的患者中,血清IgG4水平较高,这表明了不同的疾病特征.
科学领域:
- 类风湿病学 类风湿病学
- 肺部病理学 肺部病理学
- 放射学 放射学是一门学科.
背景情况:
- 免疫球蛋白G4相关疾病 (IgG4-RD) 是一种多系统纤维炎症疾病.
- Pleuropulmonary 参与是公认的,但其频率和特定的CT发现需要进一步的表征.
研究的目的:
- 为了确定患有IgG4-RD的患者中多肺CT发现的频率.
- 为了比较IgG4-RD患者的临床和实验室特征,有或没有多肺肺部参与.
主要方法:
- 从IgG4-RD患者队列中进行的胸部CT扫描的回顾性分析.
- 肺病变被分为四种亚型:结节,磨砂玻璃不透明,间隙-膜和支气管血管干扰.
- evaluation of pleural and mediastinal involvement. 评价腹腔和中腔的卷入情况. 评价腹腔和中腔的卷入情况.
主要成果:
- 在28名患者中有61%的患者观察到肺部干扰.
- 支气管血管干扰 (100%) 和间歇性-气泡膜干扰 (59%) 是最常见的亚型.
- 没有发现显著的人口,临床或实验室差异,除了在没有肺部参与的患者中较高的血清IgG4水平 (p=0.022).
结论:
- 在IgG4相关的疾病中,CT主要发现的肺参与包括隔膜加厚和支气管血管组织增加.
- 患有或没有肺病患的患者之间的临床和实验室表现相似,除了血清IgG4水平.
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