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Updated: Jun 1, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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环醇的homo-Mannich反应:天然产品合成的多功能工具

Tao Zhou1, Qiuyuan Tan1, Dan Jiang1

  • 1Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, China.

Accounts of chemical research
|January 17, 2025
PubMed
概括

这项研究引入了一种新型的homo-Mannich反应,使用cycclopropanol,一种多用途的homoenolate等价物,用于合成有价值的胺碳化合物. 这种方法可以有效地获得复杂的类天然产品.

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