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Updated: Jun 1, 2025

A Murine Cell Line Based Model of Chronic CDK9 Inhibition to Study Widespread Non-Genetic Transcriptional Elongation Defects TEdeff in Cancers
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通过防止SPT5酸化,LEDGF/p75促进了转录暂停

Chenghao Guo1,2, Shuhan Si1, Haitong Fang1

  • 1Department of Hematology, Zhongda Hospital, Key Laboratory of Developmental Genes and Human Disease, School of Life Science and Technology, Southeast University, Nanjing 210096, China.

Science advances
|January 17, 2025
PubMed
概括

LEDGF/p75和超延长复合体 (SEC) 合作调节SPT5.

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