在接受下前进装置治疗的患者中,治疗中出现的中央睡眠呼吸暂停
Hédi Aïssani1, Jean-Daniel Kün-Darbois2, Clémence Moreau3
1CHU Angers, Department of Maxillo-facial surgery, F-49933, Angers, France.
Sleep medicine
|January 17, 2025
概括
治疗引起的中央睡眠呼吸暂停 (TECSA) 很少发生在下前进装置 (MAD) 中,影响患者的比例高达5.04%. 与MAD相关的TECSA患者可能会经历较差的生活质量和增加的嗜睡.
科学领域:
- 睡眠医学 睡眠医学
- 呼吸系统医学 呼吸系统医学
- 牙科 睡眠医学 睡眠医学
背景情况:
- 治疗出现的中央睡眠呼吸暂停 (TECSA) 是积极气道压力治疗的已知并发症.
- 对于因阻塞性睡眠呼吸暂停综合征 (OSAS) 接受 mandibular advancement devices (MADs) 治疗的患者,其发生率和临床相关性不太清楚.
- 这项研究调查了MAD使用者的TECSA.
研究的目的:
- 为了评估TECSA在接受MAD治疗的患者中的患病率.
- 在这个人群中识别与TECSA相关的风险因素.
- 评估TECSA的临床相关性,包括它对生活质量和嗜睡的影响.
主要方法:
- 包括139名用定制可定位MAD治疗的OSAS患者.
- 睡眠记录被用来识别TECSA.
- 使用问卷 (QD2A,SF-36,ESS) 进行了TECSA和非TECSA组之间的比较分析,以评估临床相关性.
主要成果:
- 根据使用的定义,TECSA的患病率在0%至5.04%之间.
- 在人口统计数据,睡眠结构或并发症方面没有发现显著差异,尽管在TECSA组中发现了较高动脉高血压的趋势.
- 患有TECSA的患者表现出更高的基线和随访爱普沃思睡眠度量得分的趋势,以及显著较低的SF-36一般健康得分.
结论:
- TECSA是一种罕见但可能发生的并发症,患者接受MAD治疗OSAS.
- 需要在更大的队列中进行进一步的研究,以充分阐明风险因素.
- 与MAD相关的TECSA可能与睡眠和生活质量方面较差的主观结果有关.
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