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Updated: Jun 1, 2025

High-throughput Screening for Chemical Modulators of Post-transcriptionally Regulated Genes
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Published on: March 3, 2015

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通过合理的5'UTR和3'UTR组合设计优化mRNA翻译效率

Ting Li1, Gangfeng Liu2, Guolong Bu1

  • 1State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.

Gene
|January 17, 2025
PubMed
概括

研究人员通过设计新的未翻译区域 (UTR) 来优化信使RNA (mRNA) 疗法. 结合特定的5'UTR和3'UTR序列,显著提高了用于增强mRNA治疗的蛋白质生产.

关键词:
3",UTR"可以使用.5′UTR 5′UTR是指UTR的时间.翻译效率 翻译效率 翻译效率这是一种UTR组合.它们是mRNARNA.

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