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Updated: Jun 1, 2025

Lineage Tracing and Clonal Analysis in Developing Cerebral Cortex Using Mosaic Analysis with Double Markers MADM
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单向的MCM转移远离ORC驱动原产地许可证

Agata Butryn1, Julia F Greiwe1,2, Alessandro Costa3

  • 1Macromolecular Machines Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.

Nature communications
|January 17, 2025
PubMed
概括

细胞的复制性酶 (MCM) 载荷机制是使用冷EM. 由MCM驱动的ATPase驱动的DNA转移远离起源识别复合体 (ORC) 对于MCM加载至关重要.

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Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells06:09

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Checkpoints throughout the cell cycle serve as safeguards and gatekeepers, allowing the cell cycle to progress in favorable conditions and slow or halt it in problematic ones. This regulation is known as the cell cycle control system.
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Mitochondrial protein import is powered by two distinct energy sources: ATP hydrolysis and electrochemical potential across the inner membrane. Newly synthesized precursors are bound by cytosolic chaperones of the Hsp70 family, which guide them to the import receptors on the mitochondrial surface. Utilizing the energy of ATP hydrolysis, Hsp70 chaperones transfer these precursors to the TOM receptors on the mitochondrial outer membrane.
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